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Base Units.While the ratios are pretty straightforward, the base unit for phyto-estrogens is extremely hard to estimate. Essentially, I have worked backwards from what appear to be unwieldy amounts (During the proliferative phase) and then reduced to a standard level. to establish a common denominator. I would really welcome any feedback from nutritionists, herbalists, endocrinologists or informed amateurs in this area. I freely admit, that at this point, I am using educated guesses as to estimate what a base unit should comprise with phyto estrogens. I would encourage experts in this field to make suggestions, since it is a worthwhile endeavor to reduce chemical intake from plant source or otherwise. Pharmaceutical DosesPharmaceutical Estradiol is prescribed anywhere from 4-8 mg per diem in pre-op transsexuals. This is a highly concentrated form of Estrogen, and used alone, creates the estrogenic effects most are seeking. Based on the theoretical model of cycling to mimic the natural menstrual cycle, this would mean generally lower levels of Estradiol in the system. This would translate to: The Assumptions I have made for phyto estrogenic base unit.All doses are consumed with 1 - 2 cups of soy/grenadine/fenugreek. This creates a "baseline" upon which the other plants ride. Marginal estrogen/progesterone dominance is normal for all parts of the cycle, with the exception of the latter half of the proliferative phase. Coincidentally, the "3 sisters of estrogen" - Estradiol, estrone and estriol are well represented in this drink. Estrogen SupplementsPhyto estrogenic supplements 'ride' on this baseline and are namely. Saw Palmetto and Red clover. The choice of plant source is not accidental Saw Palmetto for example is additionally an anti-androgen. Further, Saw Palmetto, Red Clover (and soy) are rich in B -sitosterol and occur in concentrations high enough to produce estrogenic activity. Progesterone SupplementsThe phyto progesteronic supplement is wild Yam root. Wild Yam is a bit of a paradox...there is some controversy over its progesterone like effects. The argument being that while it is the source for commercially available progesterone, the wild yam extract has been processed in a way that the human body can not. Perhaps I am a little cynical, but given that the primary information source is an industry that makes many millions of dollars supporting that point of view...frankly, I don't buy it. There is less well funded data that suggests that the human body can in fact process the constituent parts into meaningful progesterones...perhaps not as efficiently as a factory, but meaningful none the less. Given the very low toxicity levels of wild yam. (about the only way to die from it is if a crate of them fall on your head)...I have chosen a fairly high level during the latter proliferative phase.
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